EMB-15 for advanced solid tumors without standard treatment
Part of Cancer clinical trials.
This is a first-time-in-humans study testing a new drug called EMB-15 for patients with advanced cancers that have spread or cannot be surgically removed. The drug targets proteins called ALPP/ALPG, which may help your immune system fight cancer cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of advanced or metastatic solid tumor (cancer that has spread) without an available standard treatment option
- You are 18 years or older and able to provide informed consent
- You have a life expectancy of at least 3 months and good overall health (ECOG performance status 0 or 1)
- You can provide a tumor tissue sample collected within the past year
- You have adequate blood counts and organ function (liver, kidney, heart)
- You have not received cancer treatment, radiation, or investigational drugs within the past 4 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new type of immune cell therapy designed to target and attack cancer cells that have a specific marker called ALPP. It is for people with advanced solid tumors who have not responded to or cannot have standard treatments.
This Phase 1 trial tests EMB-07, a new treatment, in people with advanced or hard-to-treat solid tumors or certain relapsed/refractory lymphomas. The goal is to find a safe dose and learn whether it can shrink tumors.
This trial tests an experimental drug called SPGL008 in people with advanced solid tumors that have spread or cannot be removed. It is a first-in-human study to learn about safety, dosing, and how the drug works.
This trial tests a new drug called PLT012 for people with advanced solid tumors. It is the first study in humans, so doctors will see if the drug is safe and how the body handles it.
This trial tests a new drug, ALMB-0168, for people with solid tumors that have spread to the bones and who have already tried standard treatments without success. It focuses on breast cancer with only bone spread and prostate cancer with bone metastases that are no longer responding to hormone therapy.
This trial tests a new drug, ALK201, in people with advanced solid tumors that have not responded to other treatments. It aims to see if the drug is safe and can shrink tumors.
Hear when a new Locally Advanced or Metastatic Solid Tumors trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.