Saliva Tests to Predict Reflux After Weight-Loss Surgery
Part of Cancer, Digestive system clinical trials.
This study tests whether certain substances in your saliva can predict who will develop acid reflux after sleeve gastrectomy (a weight-loss surgery that makes your stomach smaller). If we can predict this early, doctors may be able to prevent it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and scheduled for sleeve gastrectomy at a participating hospital
- Your BMI is 50 kg/m² or lower, and your obesity surgery has been approved by a multidisciplinary committee
- You have no previous history of severe acid reflux, Barrett's esophagus, or other esophageal diseases
- You have never had esophageal surgery or other bariatric (weight-loss) procedures
- You are willing to provide saliva samples and attend follow-up visits
- You are not pregnant, breastfeeding, or taking medications that affect bile acid metabolism
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at how to predict who will develop acid reflux after a “stomach sleeve” operation. It may help doctors choose the safest plan before surgery and better prevent reflux afterward.
This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.
This study looks at how digestion works after weight-loss surgery. Volunteers may be people with obesity or those who had gastric bypass or sleeve gastrectomy at least a year ago. The goal is to learn more about gut function after surgery.
This study compares two weight-loss surgeries—gastric bypass and sleeve gastrectomy—to see which one causes less acid reflux afterward. It may help you by tailoring which surgery is better for people with reflux symptoms before surgery.
This study looks at whether a treatment plan called “Sleeve-pex” can reduce heartburn and reflux after sleeve gastrectomy. If you’re planning this surgery and can complete symptom questionnaires, you may be able to join and help compare outcomes between groups.
This study checks whether a surgical “fix” (omentumpexy) can reduce acid reflux after sleeve gastrectomy. It’s mainly for adults having sleeve surgery who have a higher-risk body weight and related health problems.
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