Clinical trials
Sleeve Gastrectomy clinical trials
Below are recruiting sleeve gastrectomy clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06783751Recruiting
New surgical method to reduce acid reflux after weight loss surgery
This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.
Orange, CaliforniaAges 18–65 - NCT04994665Recruiting
Test of fixing the stomach to reduce reflux after sleeve surgery
This study checks whether a surgical “fix” (omentumpexy) can reduce acid reflux after sleeve gastrectomy. It’s mainly for adults having sleeve surgery who have a higher-risk body weight and related health problems.
BayonneAges 18 years+ - NCT05211375RecruitingPhase 3
Compare two weight-loss surgeries for type 2 diabetes control
This Phase 3 trial compares sleeve gastrectomy versus a different bypass-style operation to improve blood sugar in adults with type 2 diabetes. It may help some people lower blood sugar and diabetes medication needs, but you must meet specific safety and health criteria.
Seongnam-siAges 18 years+ - NCT05704348Recruiting
Test to reduce reflux after sleeve stomach surgery
This study looks at whether a treatment plan called “Sleeve-pex” can reduce heartburn and reflux after sleeve gastrectomy. If you’re planning this surgery and can complete symptom questionnaires, you may be able to join and help compare outcomes between groups.
FørdeAges 18 years+ - NCT06425016Recruiting
Robot-assisted vs. traditional sleeve gastrectomy
This study compares two types of weight-loss surgery: one done with the help of a robot and the other done by hand (laparoscopic). Both are types of sleeve gastrectomy, where the stomach is reduced in size. If you qualify for sleeve gastrectomy, this trial may help doctors learn which method works better.
Cleveland, OhioAges 18–70 - NCT06474637Recruiting
Powered handle sleeve gastrectomy study
This trial tests a new powered handle tool that doctors use during sleeve gastrectomy surgery to help people lose weight. It is for patients having this surgery for the first time.
KaunasAges 18–65 - NCT07230769Recruiting
Bougie size effect on stomach sleeve surgery results
This trial compares different bougie sizes during laparoscopic sleeve gastrectomy to see which works best. It's for adults with obesity (BMI 30+ with related health issues or BMI 35+), who have not had prior stomach surgery and have minimal acid reflux.
Alexandria, Alexandria GovernorateAges 18–70 - NCT07038148Recruiting
Single-stage conversion of gastric bypass to sleeve gastrectomy
This trial is testing a single surgery that converts a previous gastric bypass into a sleeve gastrectomy, and checking if there is a higher risk of leaks. It may be an option for people who need this change and are in good overall health.
Cairo, Old CairoAges 18–70 - NCT06970678RecruitingPhase 1/Phase 2
A new way to ease pain and speed recovery after sleeve gastrectomy
This study tests whether adding two pain-management methods—a sedative infusion and a nerve block around the stomach—can help you recover faster and more comfortably after sleeve gastrectomy surgery. If you're eligible, you'll receive the extra treatment on top of standard anesthesia.
AlexandriaAges 18–60 - NCT05330910Recruiting
Repair of a stomach valve during sleeve weight-loss surgery
This trial tests whether doing a specific repair near the stomach valve (the gastroesophageal junction) during laparoscopic sleeve gastrectomy can help people with a loose valve. It is aimed at adults who have a particular endoscopy finding (Hill grade III) and choose this weight-loss surgery.
SingaporeAges 21–65 - NCT05611697Recruiting
Compare two weight-loss surgeries for severe obesity
This trial compares two types of bariatric (weight-loss) surgery to see which helps people with severe obesity lose weight and stay healthy. You might be eligible if you’re between 20 and 60 and are already being referred for bariatric surgery after prior unsuccessful weight-loss attempts.
Tønsberg, VestfoldAges 20–60 - NCT02937649Recruiting
Testing a bougie tool during sleeve stomach surgery
This trial checks a specific surgical measuring tool (“bougie”) used during sleeve gastrectomy (weight-loss stomach surgery). It may help the surgical team improve how the sleeve is formed while keeping safety in mind.
Boulogne-BillancourtAges 18–70 - NCT06515691Recruiting
Nerve block for pain after weight loss surgery
This study tests a nerve block (an injection near the nerves) to see if it helps reduce pain after laparoscopic sleeve gastrectomy. The block is called a modified thoracoabdominal nerve plane block, and it may lead to better pain control and recovery.
Istanbul, BagcilarAges 18–65 - NCT07397572Recruiting
Iron pills and anemia after sleeve gastrectomy
This study tests whether giving iron supplements after sleeve gastrectomy surgery helps prevent or treat anemia. It may be a good fit if you are planning to have this weight-loss surgery and can commit to 6 months of follow-up.
Cairo, Al-Manial CairoAges 18–65 - NCT06868992Recruiting
Study of MASH and cell changes in weight-loss surgery
This study looks at a possible link between MASH (liver inflammation with fat buildup) and tiny cell structures that help liver cells work. Researchers want to understand this better in people having weight-loss surgery, where a small liver sample will be taken.
Lyon, FranceAges 18–99 - NCT04411823Recruiting
Predicting reflux after stomach sleeve surgery
This trial looks at how to predict who will develop acid reflux after a “stomach sleeve” operation. It may help doctors choose the safest plan before surgery and better prevent reflux afterward.
Orlando, FloridaAges 18 years+ - NCT07461610Recruiting
Stool analysis after sleeve gastrectomy vs gastric bypass
This trial compares changes in stool after two common weight-loss surgeries: sleeve gastrectomy and gastric bypass. It aims to understand how these surgeries affect digestion and gut health.
Cairo, Al-Manial CairoAges 18–60 - NCT07274215Recruiting
Nerve block injection for pain and nausea after sleeve gastrectomy
This study tests a special numbing injection (called a paragastric block) to see if it reduces pain and nausea after sleeve gastrectomy surgery. If you are having this weight-loss surgery, the injection might help you feel better and recover more comfortably.
IstanbulAges 18–65 - NCT07600411Recruiting
Weight-loss surgery and mood: comparing two surgical approaches
This study follows patients undergoing one of two common weight-loss surgeries (sleeve gastrectomy or gastric bypass) to see how each affects binge eating, depression, and anxiety. Researchers want to understand which surgery may help improve both weight and mental health outcomes.
Cairo, Al-Manial CairoAges 18–60 - NCT05576116Enrolling by invitation
Bariatric surgery plus pancreas transplant after kidney transplant
This trial studies whether adding bariatric (weight-loss) surgery and a pancreas transplant can improve health in people with long-term type 2 diabetes who already received a kidney transplant. It may help with blood sugar control and related metabolic health, while also needing careful safety screening for kidney function and blood vessel health.
Toronto, OntarioAges 18–50 - NCT07158008Recruiting
Weight loss surgery for people with obesity and heartburn
This study compares two weight-loss surgeries for people who have both obesity and severe heartburn or GERD. One surgery combines part of the stomach removal with an anti-reflux wrap, while the other reroutes the stomach to help with weight loss and reflux.
KrakowAges 18–65 - NCT04643262Enrolling by invitation
Looking back at bariatric surgery outcomes in obesity
This study looks back at people who had sleeve gastrectomy (a weight-loss operation) and compares results and complications. It may be a fit if you match the study’s age, weight, and health history, though it’s a “retrospective” review, so it mainly uses past records.
Ages 18–68 - NCT07637357Recruiting
How anesthesia affects thinking after weight-loss surgery
This study looks at how different types of anesthesia used during sleeve gastrectomy (a weight-loss surgery) may affect your memory and thinking skills after the operation. Researchers want to understand which anesthesia approach is safest for your brain.
Istanbul, SancaktepeAges 18–65 - NCT06970626RecruitingPhase 2/Phase 3
Comparing pain relief methods after sleeve gastrectomy
This study compares two ways to manage pain after laparoscopic sleeve gastrectomy: one uses a medication called dexmedetomidine given through an IV, and the other uses a combination of nerve blocks (TAP block and paragastric block) to see which leads to a better recovery.
AlexandriaAges 20–60
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Common questions
- Are there clinical trials for sleeve gastrectomy?
- Yes. Clin2 currently lists 71 recruiting sleeve gastrectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sleeve gastrectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sleeve gastrectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.