Lubricin-inspired Treatment for Knee Osteoarthritis Pain
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests a new lubricin-inspired treatment designed to help people with moderate to severe knee osteoarthritis who haven't gotten enough pain relief from standard treatments like NSAIDs or physical therapy. The study aims to see if this approach can reduce knee pain and improve function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 40 or older
- Knee osteoarthritis confirmed on X-ray (grades 2–4 severity)
- Moderate to severe knee pain (at least 15 days per month) that hasn't improved enough with first-line treatments like NSAIDs or physical therapy
- Willing to keep your current pain medications stable throughout the trial and stop taking 'as needed' pain pills (except rescue medication)
- No knee surgery or steroid injections in your target knee within the past 6 months, and no surgery planned in the next 8 months
- Able to understand study instructions and attend scheduled clinic visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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