Knee injection for knee osteoarthritis pain
Part of Bones, joints & muscles, Pain clinical trials.
This study tests an experimental injection called GNSC-001 given directly into the knee to see if it can reduce pain and improve knee function in people with knee osteoarthritis. If you join, you'll have one injection and then be followed for a year, and you'll need to stop your usual knee pain medicines during the study.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have knee osteoarthritis in the study knee, confirmed by X-ray.
- You've had knee pain for at least 6 months.
- Your average knee pain in the last day is between 5 and 9 on a 0-10 scale.
- You have signs of inflammation or fluid in the knee on imaging.
- You must be willing to stop taking all pain medicines for knee OA, including over-the-counter NSAIDs.
- You cannot have other inflammatory conditions like rheumatoid arthritis or gout.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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