Gut Health and Rotavirus Vaccine Response in Adults
Part of Digestive system, Immune system & allergy, Infections clinical trials.
This study examines how the health of your digestive system affects how well your body responds to an oral rotavirus vaccine (a vaccine given by mouth to protect against rotavirus infection). You'll have two endoscopy procedures—a camera test to look inside your digestive tract—and provide samples to help researchers understand this connection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 50 years old
- You live in Lusaka district, Zambia, and can attend scheduled visits
- You are willing to have two endoscopy procedures (a camera tube inserted to examine your gut) with sample collection
- You do not have an active digestive disease requiring treatment, such as stomach ulcers or active bleeding
- You are not pregnant, breastfeeding, or planning to become pregnant in the 30 days after vaccination
- You do not have a severe immune system problem, uncontrolled high blood pressure, or heart/lung disease that would make endoscopy unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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