Light therapy to boost immune treatment for advanced melanoma
Part of Cancer, Skin clinical trials.
This study tests whether special light therapy timed to your body's natural rhythms can improve how well your immune cells (called TIL therapy) fight advanced melanoma. You must already be enrolled in standard TIL therapy and have progressed despite previous immunotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older and able to read and understand English
- Advanced melanoma that stopped responding to immune checkpoint inhibitor drugs (like nivolumab or pembrolizumab)
- Already approved by your doctor for standard TIL therapy (lifileucel/Amtagvi)
- Good enough health status to tolerate the treatment (ECOG score of 0, 1, or 2)
- No recent travel across time zones, night shift work, or sleep medications in the past 2 weeks
- No untreated sleep apnea, history of bipolar disorder, migraines triggered by light, or eye conditions worsened by bright light
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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