Electrical stimulation for depression
Part of Mental health clinical trials.
This trial tests a non-invasive treatment that uses small electrical pulses to help activate facial muscles involved in smiling, which may improve mood in people with depression. It involves 20 sessions over about two weeks, plus a four-week follow-up.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have been diagnosed with major depressive disorder (unipolar) and are currently having a depressive episode without psychotic features.
- You have tried fewer than two depression treatments that didn't work (so you are not considered treatment-resistant).
- Your depression medication or therapy has been stable for at least 4 weeks before the study, and you agree not to change it during the study.
- You do not have a history of seizures, facial nerve damage, or metal implants in your mouth.
- You are not currently experiencing suicidal thoughts or plans.
- You can understand and follow instructions in English.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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