Clin2
NCT07706348Possibly a fitRecruiting

Pain relief with ondansetron and lidocaine after abdominal cancer surgery

Acue Postoperative Pain

Part of Pain clinical trials.

This trial tests if rinsing the belly with ondansetron (a nausea medicine) and lidocaine (a numbing medicine) during surgery can reduce pain afterward. It is for people having major lower abdominal cancer surgery who are otherwise healthy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
20 people
Ages
20 years to 70 years
Study type
Interventional

Who can take part

  • You are scheduled for major lower abdominal cancer surgery.
  • You are in good health overall (classified as ASA I or II).
  • Your body mass index (BMI) is below 30.
  • You do not have allergies to ondansetron or lidocaine.
  • You have not used opioids (strong painkillers) or been addicted to drugs.
  • You have not been taking benzodiazepines (anti-anxiety medicines) long-term.
  • You do not have serious heart, lung, kidney, or liver disease, or a history of stroke or psychiatric illness.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05450055Not yet recruiting
Numbing medicine for ovarian cancer surgery pain

This trial tests whether giving a numbing medicine (lidocaine) into the belly during ovarian cancer surgery can help reduce pain after the operation. If it works, you might have less pain and need fewer painkillers after surgery, helping you recover more comfortably.

Beijing
NCT06850740Enrolling by invitation
Spinal ondansetron for hernia repair pain relief

This trial tests if adding ondansetron to standard spinal anesthesia during hernia surgery can provide better pain relief. It may help you need less pain medicine after the procedure.

Ismailia
NCT07869173Not yet recruiting· Phase 3
Lidocaine infusion for chronic pain after emergency abdominal surgery

This trial tests whether giving a medicine called lidocaine through a vein during emergency abdominal surgery can reduce long-term pain after the operation. Lidocaine is a common numbing medicine, and this study aims to see if it helps prevent chronic pain that some people experience after surgery.

Angers
NCT07632144Not yet recruiting
Comparing two medicines to reduce pain from anesthesia injection

This study compares two medicines—ondansetron (usually used for nausea) and lidocaine (a numbing medicine)—to see which one better reduces the pain you might feel when the anesthesia drug propofol is injected into your vein. If you are having planned surgery with general anesthesia, you may be able to help find a more comfortable way to start anesthesia.

Tunis
NCT06297499Recruiting· Phase 1
Testing ondansetron to prevent itching after C-section

This trial tests if giving ondansetron before spinal anesthesia can prevent itching that often happens after a C-section. It may help you feel more comfortable during recovery.

Detroit, Michigan
NCT07263165Not yet recruiting
Pain relief study for upper abdominal cancer surgery

This study tests whether adding a sedative medicine to the numbing medication used in a nerve block can improve pain relief after upper abdominal cancer surgery. It may help reduce pain and the need for strong painkillers after the operation.

Hear when a new Acue Postoperative Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.