Nasal spray with exosomes for chronic sinus inflammation
Part of Ear, nose & throat clinical trials.
This early-stage trial tests a new nasal spray containing exosomes (tiny cell particles), azelastine (an allergy and inflammation fighter), and interferon (an immune booster) for chronic sinusitis—a long-lasting sinus infection. The spray is designed to reduce sinus inflammation and symptoms during flare-ups without needing systemic antibiotics or steroids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–65 years old
- Diagnosed with chronic rhinosinusitis (long-lasting sinus inflammation) lasting more than 12 weeks
- Moderate-to-severe sinus inflammation visible on nasal endoscopy (camera exam) and symptom score of at least 30
- Stable nasal symptoms in the past month, or occasional flare-ups that do not require oral antibiotics or steroids
- No sinus surgery in the past 6 months and no anatomical problems needing future surgery
- Not allergic to poloxamer, chitosan, azelastine, or interferon
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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