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NCT07635459Possibly a fitNot yet recruiting

Nasal spray with exosomes and anti-inflammatory medicines for chronic sinusitis

Chronic Rhinosinusitis Without Polyps

Part of Ear, nose & throat clinical trials.

This trial tests a new nasal spray that combines exosomes (tiny cell messengers), azelastine (an antihistamine), and interferon (a protein that helps fight infections) for people with chronic sinusitis. It aims to reduce symptoms and improve your sinus condition.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
108 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You must be between 18 and 65 years old.
  • You must have had chronic sinusitis for more than 12 weeks.
  • Your symptoms must be stable in the last month, or if you have a flare-up, it must not require strong antibiotics or steroid pills.
  • You must not have used steroid nasal sprays, antihistamines, or other allergy medications in the past 2 weeks.
  • You must not have nasal polyps, have had sinus surgery in the last 6 months, or have serious health problems like diabetes, high blood pressure, or an autoimmune disease.
  • You must be willing to give your written consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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