Testing a new tablet for chronic sinusitis without nasal polyps
Part of Ear, nose & throat clinical trials.
This trial tests an experimental tablet (HTMC0658) for people with chronic sinusitis that hasn't improved with standard nasal spray. You may join if your symptoms are moderate to severe and you've been using a stable dose of mometasone spray for at least 4 weeks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- Your body mass index (BMI) is at least 18.5.
- You have had sinusitis symptoms for more than 12 weeks, and a doctor confirmed it with a scope or CT scan showing inflammation in both sides of your sinuses.
- You have moderate to severe stuffy nose (score of at least 2 out of 3) and a total of at least 5 points for stuffy nose, runny nose, and facial pain/pressure.
- You have been using a stable daily dose of mometasone furoate nasal spray for at least 4 weeks before starting the trial.
- If you have asthma or COPD, it must be stable without flare-ups or emergency treatment for the last 3 months, and your inhaled steroid dose must be steady.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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