Clin2
NCT07640997Likely a fitRecruiting

Real-world study of aflibercept for age-related macular degeneration

Neovascular Age-Related Macular Degeneration (nAMD)

Treatments studied

Part of Eyes & vision clinical trials.

This study follows patients receiving aflibercept 8 mg injections in the eye to treat wet age-related macular degeneration (nAMD), a condition that blurs central vision. The goal is to understand how well this treatment works and its safety in routine medical practice.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
300 people
Ages
50 years and older
Study type
Observational

Who can take part

  • You are 50 years or older
  • You have been diagnosed with wet age-related macular degeneration (nAMD)
  • Your eye pressure in the study eye is 25 mmHg or lower
  • Your other eye has not received anti-VEGF injections (except aflibercept) within the last 28 days
  • You have no eye infections or severe inflammation in the study eye
  • You are not allergic to aflibercept

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07489586Not yet recruiting· Phase 3
Comparing a new injection to aflibercept for wet macular degeneration

This study tests a new eye injection (called QL1207H) against aflibercept, a standard treatment for wet macular degeneration. The goal is to see if the new drug is as effective in improving vision and reducing fluid in the eye.

NCT07798375Not yet recruiting· Phase 2
Eye injection for wet age-related macular degeneration

This trial tests a new medicine called VIS-101, given as an injection into the eye, for people with wet age-related macular degeneration (AMD) who have not been treated before. The goal is to see if it can reduce fluid buildup and improve vision while being safe.

NCT07064759Recruiting· Phase 3
Gene therapy injection for wet age-related macular degeneration

This trial tests a one-time gene therapy injection (4D-150) for wet AMD. It might help reduce the need for frequent anti-VEGF eye injections by targeting the underlying cause of new blood vessel growth.

Scottsdale, Arizona
NCT07776522Recruiting· Phase 2
Gene therapy for wet age-related macular degeneration

This trial tests a one-time gene therapy injection under the retina for people with wet age-related macular degeneration (AMD), which causes blurry vision from abnormal blood vessels. It aims to reduce the need for frequent eye injections by delivering a treatment that may help the eye produce its own medicine.

Beijing, Beijing Municipality
NCT06839339Not yet recruiting· Phase 2
Eye injection for wet age-related macular degeneration

This trial tests a new eye injection called AL-001 for people with wet age-related macular degeneration (AMD), a condition that causes blurry vision. The injection aims to stop the growth of abnormal blood vessels in the eye and improve vision.

Beijing
NCT07728981Not yet recruiting· Early Phase 1
Aflibercept for untreated wet age-related macular degeneration

This study tests a higher dose of a drug called aflibercept, given as eye injections, for people with untreated wet age-related macular degeneration (AMD). The goal is to see if it can improve vision and how often it needs to be given.

Hear when a new Neovascular Age-Related Macular Degeneration (nAMD) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.