Clin2
NCT07644325Possibly a fitRecruiting

Comparing Two Biopsy Methods for Carpal Tunnel Amyloidosis

Carpal TunnelTransthyretin Amyloidosis

Part of Brain & nervous system clinical trials.

This study compares two small tissue samples taken during carpal tunnel surgery to see which method best detects a protein disease (transthyretin amyloidosis) that can affect nerves and the heart. If you have carpal tunnel syndrome and are having surgery, this research may help doctors diagnose related heart or nerve problems earlier.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
500 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are an adult with health insurance
  • You have been diagnosed with carpal tunnel syndrome and had nerve testing (EMG) to confirm it
  • Your doctor has decided you need carpal tunnel surgery
  • You have at least one risk factor: carpal tunnel in both hands, heart failure, irregular heartbeat, or you are elderly
  • You are able to give informed consent and are not under legal guardianship
  • Your surgery can be done using a minimally invasive method (not open surgery)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07580872Not yet recruiting
Screening for heart amyloid in bilateral carpal tunnel patients

This study looks for early signs of cardiac amyloid (a protein buildup in the heart) in people who had carpal tunnel surgery on both hands. Carpal tunnel surgery on both sides may be linked to a rare heart condition, and early detection could help prevent serious heart problems.

NCT06458374Recruiting
Heart Amyloidosis in Carpal Tunnel Surgery Patients

This study looks for people who had carpal tunnel surgery at Ålesund Hospital to check for a rare heart condition called ATTR amyloidosis. It aims to find the disease early and see how common it is.

Ålesund, Møre og Romsdal
NCT07594821Recruiting
Two approaches to carpal tunnel surgery: comparing outcomes

This study compares two surgical approaches for carpal tunnel syndrome—one that releases pressure on the median nerve in one location versus releasing it in two locations. The goal is to find out which approach works better for relieving symptoms like numbness and tingling in the hand.

Rotterdam, South Holland
NCT07576803Not yet recruiting
Needle Therapy vs Surgery for Carpal Tunnel Syndrome

This trial compares two treatments for carpal tunnel syndrome: a newer needle-based technique called hydrodissection with neuroprolotherapy versus traditional open surgery. If you've tried splints, medications, or physical therapy without relief, this study tests which approach works better and is safer.

Recife, Pernambuco
NCT07752797Recruiting
Ultrasound and nerve tests for carpal tunnel syndrome

This study looks at how ultrasound, nerve tests, and hand function relate to carpal tunnel syndrome. It aims to improve understanding of the condition and may help guide future treatment decisions.

Küçükçekmece, Istanbul
NCT07614425Recruiting
Surgery for Carpal Tunnel Syndrome Study

This study tests surgical treatment for carpal tunnel syndrome—a condition where a nerve in your wrist gets compressed, causing numbness, tingling, or pain in your hand. You may qualify if you have confirmed carpal tunnel syndrome and conservative treatments like splints haven't helped.

Helsinki

Hear when a new Carpal Tunnel trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.