Clinical trials
Carpal Tunnel clinical trials
Below are recruiting carpal tunnel clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07723313RecruitingEarly Phase 1
Amniotic membrane and secretome for carpal tunnel release
This trial tests whether adding a special membrane (amniotic membrane) and a natural healing fluid (secretome) to standard carpal tunnel release surgery can improve hand function better than surgery alone. It may be a good option if your wrist pain and numbness haven't gone away with other treatments.
Denpasar, BaliAges 18 years+ - NCT04460521RecruitingPhase 4
NAC pills and night splints for carpal tunnel without surgery
This trial tests whether N-acetylcysteine (NAC) along with wearing a night wrist splint can improve symptoms of mild to moderate carpal tunnel syndrome. It’s designed for people who want a non-surgical option.
Halifax, Nova ScotiaAges 18 years+ - NCT05372393Recruiting
Carpal tunnel surgery with local anesthesia, with or without nerve block
This study compares two ways of giving pain control during carpal tunnel release surgery: local anesthesia alone versus local anesthesia plus a targeted nerve block. It may help find the safest and most comfortable option for people having carpal tunnel surgery.
Kuopio, Northern SavoniaAges 18 years+ - NCT05431101Recruiting
Absorbable versus non-absorbable stitches after carpal tunnel surgery
This study compares two types of stitches used to close the skin after carpal tunnel release surgery. It may help show which stitch type leads to better healing and comfort afterward.
ApeldoornAges 18 years+ - NCT06440070Recruiting
Ultrasound-guided needle thread release for carpal tunnel
This trial tests a new, less invasive way to release the tight ligament in the wrist that causes carpal tunnel syndrome. It uses ultrasound to guide a curved needle and thread to cut the ligament, which may lead to less pain and faster recovery.
Guangzhou, GuangdongAges 40–70 - NCT07134361Recruiting
Ultrasound study for carpal tunnel syndrome
This study uses hand ultrasound to evaluate carpal tunnel syndrome before and after surgery. It may help doctors understand how the wrist changes after treatment.
São Paulo, São PauloAges 18 years+ - NCT07324005Recruiting
Ultrasound-guided carpal tunnel release and injection for carpal tunnel syndrome
This trial tests a new treatment for carpal tunnel syndrome that uses ultrasound to guide a needle to release a tight ligament in the wrist and inject a sugar-water solution around the nerve. This may help relieve pain and numbness without surgery.
TaipeiAges 20–80 - NCT07594821Recruiting
Two approaches to carpal tunnel surgery: comparing outcomes
This study compares two surgical approaches for carpal tunnel syndrome—one that releases pressure on the median nerve in one location versus releasing it in two locations. The goal is to find out which approach works better for relieving symptoms like numbness and tingling in the hand.
Rotterdam, South HollandAges 18 years+ - NCT07614425Recruiting
Surgery for Carpal Tunnel Syndrome Study
This study tests surgical treatment for carpal tunnel syndrome—a condition where a nerve in your wrist gets compressed, causing numbness, tingling, or pain in your hand. You may qualify if you have confirmed carpal tunnel syndrome and conservative treatments like splints haven't helped.
HelsinkiAges 18–75 - NCT06717477Enrolling by invitation
Improving care for carpal tunnel syndrome patients
This trial tests a new streamlined care pathway for patients with carpal tunnel syndrome. It aims to make appointments and treatments easier and faster.
Vancouver, British ColumbiaAges 18 years+ - NCT07752797Recruiting
Ultrasound and nerve tests for carpal tunnel syndrome
This study looks at how ultrasound, nerve tests, and hand function relate to carpal tunnel syndrome. It aims to improve understanding of the condition and may help guide future treatment decisions.
Küçükçekmece, IstanbulAges 18–65 - NCT07083180Recruiting
Virtual reality hypnosis for carpal tunnel surgery anxiety
This trial tests if using virtual reality and medical hypnosis before surgery can help reduce anxiety for people having their first carpal tunnel surgery.
Saint-Aubin-sur-ScieAges 18 years+ - NCT06779812Recruiting
Auriculotherapy for pain after carpal tunnel surgery
This trial tests whether auriculotherapy (needles or pressure on specific points in the ear) can help reduce pain after endoscopic carpal tunnel surgery. If you have carpal tunnel syndrome and are scheduled for this surgery, you may be able to join.
ParisAges 20 years+ - NCT07706296Recruiting
Hand function tests for carpal tunnel syndrome
This study tests whether certain hand function tests are reliable and accurate for people with carpal tunnel syndrome. It helps doctors better understand how the condition affects your hand use.
IzmirAges 18–60 - NCT03867539RecruitingPhase 4
Numbing shot and education to reduce opioids after carpal tunnel surgery
This study tests whether giving a long-lasting numbing injection (Exparel) plus education about pain management can help people avoid taking opioid pain pills after carpal tunnel release surgery. It may help reduce opioid use while still supporting comfort during recovery.
Dayton, OhioAges 18 years+ - NCT05637294Recruiting
Compare night-only versus full-time splinting for carpal tunnel
This study looks at whether wearing a wrist splint only at night works as well as wearing it full-time for carpal tunnel syndrome (CTS). It may help you find the most helpful and practical splint schedule to reduce symptoms.
HelsinkiAges 18 years+ - NCT05783245Recruiting
Cooling therapy to reduce pain after open carpal tunnel surgery
This trial studies whether cooling (cold therapy) can lessen pain after open carpal tunnel release surgery. If you’re having this surgery, your answers to questionnaires and your current pain-medication status will determine whether you can join.
Chicago, IllinoisAges 18 years+ - NCT06045013RecruitingPhase 3
Dextrose injection vs. dextrose with steroid for carpal tunnel
This study tests whether adding a common steroid (methylprednisolone) to a dextrose (sugar water) injection works better than dextrose alone for carpal tunnel syndrome. Both treatments are injected into the wrist to reduce pain and numbness.
KninAges 18–80 - NCT06239259Recruiting
Testing a Thai questionnaire for carpal tunnel diagnosis
This study is testing a new Thai-language questionnaire to see if it can accurately diagnose carpal tunnel syndrome. If you are a Thai speaker with nerve-tested carpal tunnel, you may help researchers improve how this condition is diagnosed.
Bangkok Noi, BangkokAges 18 years+ - NCT06405438Recruiting
Mud therapy vs. paraffin wax for carpal tunnel syndrome
This trial compares two non-surgical treatments—mud therapy (peloid) and paraffin wax—for people with mild to moderate carpal tunnel syndrome. It aims to see which one better eases symptoms like numbness, tingling, and hand pain.
IstanbulAges 18–65 - NCT06469931Recruiting
Ozone therapy for carpal tunnel syndrome
This trial tests if ozone injections can help people with mild to moderate carpal tunnel syndrome. It may offer a new way to treat hand numbness and pain without surgery.
ElâzığAges 18–65 - NCT06593977Recruiting
Dynavisc gel for pain after repeat carpal tunnel surgery
This trial tests a gel called Dynavisc to see if it reduces pain when placed in the wrist during a second surgery for carpal tunnel syndrome. It may help people who still have pain after their first surgery.
Leuven, BelgiumAges 18–65 - NCT06599086Recruiting
Steroid shot for carpal tunnel with split nerve
This study tests if a steroid injection helps people with carpal tunnel syndrome who also have a split median nerve (called bifid median nerve). It compares them to people without the split nerve to see if the treatment works differently.
Ankara, AnkaraAges 18–65 - NCT07660913Recruiting
Vibrating therapy for carpal tunnel syndrome
This study tests whether a gentle vibrating therapy (matrix rhythm therapy) can help relieve pain, tingling, and numbness from carpal tunnel syndrome. Participants will receive the therapy, and researchers will track if it improves hand function without surgery or drugs.
IzmirAges 18–60
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Common questions
- Are there clinical trials for carpal tunnel?
- Yes. Clin2 currently lists 65 recruiting carpal tunnel studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a carpal tunnel trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a carpal tunnel trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.