Clin2
NCT07645651Possibly a fitRecruiting

Samuraciclib for treatable basal pancreatic cancer

Resectable Pancreatic Ductal AdenocarcinomaBorderline Resectable Pancreatic Ductal AdenocarcinomaLocally Advanced Pancreatic Ductal Adenocarcinoma

Part of Cancer clinical trials.

This trial tests a new drug called samuraciclib in people with a specific type of pancreatic cancer that can be removed with surgery or is confined to the pancreas. The drug may help stop the cancer from growing, and this study aims to see if it is safe and effective before surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
15 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a specific type of pancreatic cancer (called basal) that has not spread to other organs.
  • You are 18 years or older.
  • You are physically active and able to care for yourself (ECOG 0-1).
  • Your blood counts and liver/kidney function are within normal limits.
  • You have a biopsy sample taken within the last 3 months, or are willing to have a new one taken.
  • You have not had radiation therapy for this cancer before.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04005690Recruiting· Early Phase 1
Targeted drug treatment for pancreatic cancer using pathway changes

This early-phase trial tests how well targeted medicines (and possibly an immunotherapy drug) work for people with pancreatic cancer that can’t be fully removed with surgery or has spread. It also looks at whether the treatment is safe and can shrink or control tumors by blocking specific cancer pathways.

Portland, Oregon
NCT06574620Recruiting
Studying tumor DNA and proteins in pancreatic cancer

This study is looking at genetic material and proteins from pancreatic tumors to understand how the cancer responds to treatment. It aims to help doctors choose the best therapies for patients with certain types of pancreatic cancer that can be removed surgically or that have not spread to other organs.

Vancouver, British Columbia
NCT07748611Not yet recruiting· Phase 2
Gene-guided chemotherapy for early-stage pancreatic cancer

This trial tests whether choosing chemotherapy based on a SMAD4 gene change in your tumor works better than the usual approach for pancreatic cancer that can be surgically removed. If you have the gene change, you may get a different chemotherapy combination to improve outcomes.

Chicago, Illinois
NCT07101679Recruiting· Phase 2
Study of radiation, chemo, and immunotherapy for advanced pancreatic cancer

This trial tests a combination of chemotherapy (GnP), an immunotherapy drug (serplulimab), and targeted radiation (SBRT) as a first treatment for locally advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this triple therapy can shrink the tumor and improve outcomes.

Chengdu, Sichuan
NCT06821997Recruiting· Phase 2
Chemotherapy before surgery for borderline resectable pancreatic cancer

This trial tests a combination of chemotherapy drugs (NALIRIFOX) given before surgery to shrink the tumor in people with a specific type of pancreatic cancer. The goal is to make surgery more effective and improve outcomes.

Buffalo, New York
NCT07665684Not yet recruiting· Phase 1/Phase 2
New drug combined with chemo for basal-like pancreatic cancer

This trial tests a new pill (samuraciclib) combined with standard chemotherapy for people with a specific type of advanced pancreatic cancer called basal-like. The goal is to see if the combination helps shrink or control the cancer better than chemotherapy alone.

Toronto, Ontario

Hear when a new Resectable Pancreatic Ductal Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.