Comparing Continuous vs. Shot Antibiotics for Orthopedic Surgery Infection Prevention
Treatments studied
Part of Infections clinical trials.
This study compares two ways of giving the antibiotic cefazolin during major orthopedic surgery: as a continuous drip (through an IV line over hours) versus as short shots (boluses) at certain times. The goal is to see which method better prevents infections at the surgical site.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for a major orthopedic surgery (like a hip or knee replacement, fracture repair, or spine surgery).
- You do not need another surgery within 30 days after this one.
- You do not have a weakened immune system from illness or medications.
- You are not pregnant or breastfeeding.
- You must be able to follow the study's medication schedule before, during, and after surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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