Testing how long to give antibiotics after heart surgery
Treatments studied
Part of Infections clinical trials.
This study looks at how long patients should receive an antibiotic after certain types of heart surgery, to help prevent infections. It may help find the best “duration” of antibiotic prophylaxis after surgery through the breastbone (median sternotomy).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult (18 or older) having cardiac surgery through a breastbone cut (median sternotomy).
- Your surgery is not being done for suspected or proven heart valve infection (endocarditis) or a deep breastbone wound infection.
- You do not have severe kidney problems (low kidney filtration) or need ongoing kidney machine treatments like dialysis.
- You do not have an allergy to cefazolin (a common surgical antibiotic).
- You have not had MRSA colonization or MRSA infection in the past 12 months.
- Your surgery does not involve a heart transplant or placement of a ventricular assist device/mechanical heart pump.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 study tests whether giving a broad set of preventive antibiotics before certain high-risk orthopedic surgeries lowers the chance of serious wound or bone infection. It mainly targets people who have contaminated wounds, tumor-related surgery, or known high-risk germs on the skin.
This trial tests a new way to prevent infections in people who have emergency surgery on their belly after a serious injury. The treatment is given during or right after surgery to lower the risk of infection.
This study tests different ways to give antibiotics before open-heart surgery to see which works best at preventing infections. If you are having open-heart surgery, you may be able to join and help improve care for future patients.
This study compares two ways of giving an antibiotic (cefazolin) to patients who had heart bypass surgery (CABG). The goal is to see which method better prevents surgical site infections.
This study looks at how well the antibiotic cefazolin reaches different body tissues in young children after heart surgery. It may help doctors ensure the right amount of antibiotic is given to prevent infections.
This trial compares two ways of giving an antibiotic called cefazolin during and after major orthopedic surgery to see which is better at preventing surgical site infections. If you are having major bone or joint surgery, this study might help reduce your risk of infection.
Hear when a new Surgical Site Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.