Finding the best dose for a dry eye treatment
Part of Eyes & vision clinical trials.
This trial tests different doses of a new eye drop (HUC1-394) to see which dose works best for people with moderate to severe dry eye disease. You may qualify if your dry eye symptoms have lasted at least 3 months and you have low tear production along with other signs of dry eye.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years or older
- You have had dry eye symptoms (like stinging, burning, or blurry vision) for at least 3 months
- In at least one eye, your tear production is low (Schirmer test between 1 and 10 mm in 5 minutes) and your tear film breaks up quickly (less than 7 seconds)
- You have a certain level of corneal damage (TCSS score of 4 or more on a 0–15 scale)
- Your dry eye symptoms score (OSDI) is 23 or higher on a 0–100 scale, meaning moderate to severe discomfort
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new eye drop called DFL24498 to see if it helps people with dry eye disease. You may qualify if your dry eye is moderate to severe and other treatments haven't worked well for you.
This trial tests an experimental eye drop (RCI001) to see if it's better than a placebo at relieving dry eye symptoms. It might help if you have moderate to severe dry eye and are looking for a new treatment.
This study tests two types of preservative-free eye drops to see which is more effective for people with mild to moderate dry eye disease. You will use one of the drops as directed, and the study will monitor your symptoms and eye health over time.
This study tests new artificial tear drops to see if they are safe and effective for people with dry eye disease. If you have dry eyes, these drops might help reduce symptoms and improve eye comfort.
This trial tests whether a dietary supplement called TRYPTYR can improve dry eye symptoms. You may qualify if you have moderate dry eye with certain signs, like short tear breakup time and staining on your eye surface.
This study tests an eye drop called lifitegrast for people with dry eye disease. It looks at whether the drops can improve eye comfort, reduce dryness, and help eye surface health. You may be able to join if you have had dry eye symptoms and used artificial tears in the past month.
Hear when a new Dry Eye Disease (DED) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.