Clinical trials
Dry Eye Disease (DED) clinical trials
Below are recruiting dry eye disease (ded) clinical trials, each written for real people, not researchers. We’re tracking 38 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05605314Recruiting
Study different types of dry eye in Sjögren’s
This study looks at patients with Sjögren’s-related dry eye to understand how different subtypes affect tear function and eye symptoms. It may help doctors better sort out dry eye types, which can guide more tailored care.
BeijingAges 18–80 - NCT07873697Recruiting
Gum disease and dry eye study
This study looks at whether people who have gum disease (periodontitis) are more likely to have dry eye disease. If you have both conditions, taking part could help doctors understand how they might be connected and improve care.
Sulaymaniyah, As Sulaymaniyah GovernorateAges 30–65 - NCT07780890Recruiting
Measuring eye hydration with light
This study uses a non-invasive imaging technique called Brillouin hydration mapping to measure hydration levels in different parts of the eye. It aims to help doctors better understand how hydration affects eye health and disease.
Boston, MassachusettsAges 20–79 - NCT07745062RecruitingPhase 4
Comparing two eye drops for mild to moderate dry eye
This study tests two types of preservative-free eye drops to see which is more effective for people with mild to moderate dry eye disease. You will use one of the drops as directed, and the study will monitor your symptoms and eye health over time.
La Jolla, CaliforniaAges 18 years+ - NCT07732010RecruitingPhase 4
Tryptophan for dry eye disease
This trial tests whether a dietary supplement called TRYPTYR can improve dry eye symptoms. You may qualify if you have moderate dry eye with certain signs, like short tear breakup time and staining on your eye surface.
New York, New YorkAges 18 years+ - NCT07676084RecruitingPhase 4
Over-the-counter lubricating eye drops for dry eye
This study tests whether over-the-counter lubricating eye drops can improve dry eye symptoms and eye comfort. It compares the drops to no treatment to see how well they work.
Andover, MassachusettsAges 18 years+ - NCT07656688RecruitingPhase 2
Finding the best dose for a dry eye treatment
This trial tests different doses of a new eye drop (HUC1-394) to see which dose works best for people with moderate to severe dry eye disease. You may qualify if your dry eye symptoms have lasted at least 3 months and you have low tear production along with other signs of dry eye.
SeoulAges 19 years+ - NCT07659626Recruiting
Long-term effects of Acoltremon for dry eye disease
This study tests a new medication called Acoltremon to see if it helps dry eye symptoms over a long period. If you've had dry eye for a while and used artificial tears, this trial might be for you.
Louisville, KentuckyAges 18 years+ - NCT07650708RecruitingPhase 4
Eye Dryness After LASIK Surgery With a New Dry Eye Treatment
This study tests whether a new eye lubricant called Miebo, given before LASIK vision correction surgery, reduces dry eye symptoms afterward. If you have mild-to-moderate dry eyes and need LASIK, this trial may help you stay more comfortable during your recovery.
Bozeman, MontanaAges 18 years+ - NCT06696625Recruiting
Nerve stimulation for dry eye relief
This trial tests if mild electrical pulses on the ear can reduce dry eye symptoms. If you have had dry eye for at least 6 months and meet certain eye test results, this non-drug treatment might help.
Beijing, Beijing MunicipalityAges 18–65 - NCT07605572Recruiting
GLP-1 drugs and dry eye disease in type 2 diabetes
This study tests whether a diabetes and weight-loss medication called GLP-1 receptor agonists affects dry eye disease. Researchers want to see if this medication helps or worsens dry eyes in people with type 2 diabetes and obesity.
AthensAges 18 years+ - NCT07593885Recruiting
Comparing two eye drops for moderate to severe dry eye
This study compares two preservative-free eye drops, Artelac Complete MDO and Vismed Multi, to see how well they work and how safe they are for people with moderate to severe dry eye disease. If you have dry eye due to certain conditions (like Sjögren's syndrome) and standard eye drops haven't fully helped, this study may be an option.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT07571330Recruiting
Upper Tear Drain Plug for Dry Eye After Lower Plug
This trial tests whether adding a plug to your upper tear drain (in addition to an existing lower plug) helps severe dry eye. It may improve comfort by reducing tear loss.
Monterrey, Nuevo LeónAges 18 years+ - NCT07566975Recruiting
How VEVYE Helps Dry Eye in Neuro-Eye Patients
This study tracks whether VEVYE®, a prescription eye drop, reduces dry eye symptoms and signs in people who have both a neuro-ophthalmic condition (a nerve or brain issue affecting the eyes) and dry eye disease. You'll visit the clinic for 6 months and answer questions about your eye comfort.
Houston, TexasAges 18 years+ - NCT07548632RecruitingPhase 2/Phase 3
Testing a new eye drop medicine for dry eye disease
This study tests whether licaminlimab, a new type of eye drop medicine, helps relieve dry eye disease. You'll use the study medicine for several weeks while doctors track how your symptoms and eye health improve.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07503886RecruitingPhase 2
Study of an eye drop for dry eye disease
This trial tests a new eye drop called DFL24498 to see if it helps people with dry eye disease. You may qualify if your dry eye is moderate to severe and other treatments haven't worked well for you.
Chandler, ArizonaAges 18 years+ - NCT07453212Enrolling by invitation
Food supplement for dry eye caused by meibomian gland issues
This trial tests a food supplement designed to improve dry eye symptoms by targeting the microbiome. It may help if you have dry eye due to meibomian gland problems and are not using contact lenses or certain other eye treatments.
IstanbulAges 18–65 - NCT07430735Recruiting
Moisture chamber glasses for dry eye relief
This trial tests a special pair of glasses that create a moisture chamber to relieve dry eye symptoms. It is for adults with mild to moderate dry eye who already wear glasses.
Rochester, New YorkAges 18 years+ - NCT07412860Recruiting
Eye drop test for moderate to severe dry eye
This trial tests a new eye drop (FBV_01) compared to a standard hyaluronic acid eye drop for people with moderate to severe dry eye. The goal is to see if the new drop provides better relief.
Cagliari, CAAges 18 years+ - NCT07413172RecruitingPhase 2
Testing serum tears for severe dry eye
This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.
Miami, FloridaAges 18 years+ - NCT07396441RecruitingPhase 4
Kelulut honey therapy for juvenile glaucoma
This trial tests if adding Kelulut honey to standard treatment can help protect the optic nerve in young people with juvenile open-angle glaucoma. It looks at eye pressure, nerve thickness, and dry eye symptoms.
Kota Bharu, KelantanAges 15–40 - NCT07332988Enrolling by invitation
Light therapy for dry eyes in Graves' disease
This trial tests if low-level light therapy can improve dry eye symptoms in people with Graves' disease whose dry eyes haven't gotten better with standard treatments like artificial tears.
Iași, IaşiAges 18 years+ - NCT06841471Recruiting
Role of Corneal Nerves in Dry Eye Disease
This study looks at how the nerves in the front of the eye (corneal nerves) relate to dry eye disease. It compares people with dry eye to those without to understand differences.
OltenAges 18 years+ - NCT06879782RecruitingPhase 3
Eye drops for dry eye disease: a phase 3 study
This study tests an eye drop called lifitegrast for people with dry eye disease. It looks at whether the drops can improve eye comfort, reduce dryness, and help eye surface health. You may be able to join if you have had dry eye symptoms and used artificial tears in the past month.
Beijing, Beijing MunicipalityAges 18 years+
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Dry Eye Disease (DED) trials by city
Studies with a site in or near these metro areas.
Dry Eye Disease (DED) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for dry eye disease (ded)?
- Yes. Clin2 currently lists 38 recruiting dry eye disease (ded) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dry eye disease (ded) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dry eye disease (ded) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.