TLR9 immunotherapy for stomach or appendix cancer spreading in the abdomen
Part of Cancer, Digestive system clinical trials.
This trial tests an experimental immunotherapy that targets a protein called TLR9 to help your immune system fight cancer cells that have spread into the lining of your abdomen (peritoneal carcinomatosis). It's for people with colorectal or appendix cancer that has spread this way and may also have some limited spread to the liver or lungs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must have colorectal or appendix cancer that has spread into the lining of your abdomen, called peritoneal carcinomatosis.
- Your cancer must be measurable by tests like scans, blood markers, or physical exam.
- Your doctor must expect you to live at least 12 more weeks.
- You must be able to take care of yourself most of the day (ECOG performance status 0, 1, or 2).
- Your kidney, liver, and blood counts must be within certain safe limits—your doctor will check these.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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