Clin2
NCT07667335Possibly a fitRecruiting

Combination therapy for advanced bladder cancer

Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis Urothelial CarcinomaLocally Advanced Ureter Urothelial CarcinomaMetastatic Bladder Giant Cell Urothelial CarcinomaMetastatic Renal Pelvis Urothelial CarcinomaMetastatic Ureter Urothelial CarcinomaStage IIIB Bladder Cancer AJCC v8Stage IV Bladder Cancer AJCC v8

Treatments studied

Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests a combination of three drugs for advanced bladder cancer (including cancer of the renal pelvis or ureter) that has not been treated before. The goal is to see if the combination is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
27 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have advanced or metastatic bladder, renal pelvis, or ureter cancer that hasn't been treated yet.
  • You must be 18 or older.
  • Your cancer must be measurable by scans (RECIST 1.1).
  • You need to be in adequate health (performance status 0-2) and have adequate blood, liver, and kidney function.
  • You must have a recent biopsy sample available or be willing to have a new biopsy.
  • You cannot have certain cancer types (like neuroendocrine or small cell), active autoimmune disease, or untreated brain metastases.
  • You must not have had prior systemic treatment for advanced disease, except for certain adjuvant/neoadjuvant therapy if progression occurred after 12 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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