Clinical trials
Migraine clinical trials
A neurological condition causing recurring, often disabling headaches. We’re tracking 191 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06674772Recruiting
Migraine study measuring CGRP levels by age and sex
This study measures a substance called CGRP in saliva from people with migraine and healthy volunteers to see how it changes with age and sex. It may help researchers understand migraine better.
Barcelona, BarcelonaAges 6–75 - NCT07022496RecruitingPhase 4
Can oral caffeine help with acute migraine attacks?
This trial tests whether taking caffeine by mouth can reduce the severity of a migraine attack when it happens. It may offer a simple, at-home option for people with different types of migraine.
CairoAges 18–60 - NCT06716489Recruiting
Exercise study for women with migraine
This study tests whether aerobic exercise can help reduce migraine symptoms and improve how your body senses and responds to pain. It is specifically for women aged 18–48 who have migraine headaches 3–8 days per month.
Ribeirão Preto, São PauloAges 18–48 - NCT05889624Recruiting
Study of treatments for childhood migraine headaches
This study looks at ways to help children and teens with migraine headaches by testing a care approach that includes access to evidence-based treatment. It may help if your child has frequent migraine headaches and is starting (or not already on) certain migraine-preventive medicines.
Birmingham, AlabamaAges 10–17 - NCT07642414Enrolling by invitation
Digital program combining exercises and mindfulness for migraines
This 12-week online program uses exercises, mindfulness, and digital tracking to help reduce migraines. You'll work with the app on your smartphone while staying on your current migraine medications.
San Francisco, CaliforniaAges 18 years+ - NCT07348783Recruiting
Yoga for chronic migraine and cluster headache
This study tests whether yoga-based movements can help reduce headache frequency and improve well-being in people with chronic migraine or cluster headache. You would follow online or in-person yoga instructions at home for several weeks, wear an activity tracker, and provide blood samples.
HuddingeAges 18–65 - NCT07071506Recruiting
New tools to track migraine prevention
This study tests new ways to monitor how well preventive migraine treatments are working. It is for people with chronic migraine who may be starting or already using preventive medications.
Aarhus C, DenmarkAges 18–65 - NCT06617832Recruiting
Evaluating migraine treatment designs
This trial is testing new ways to treat migraine attacks. It is for adults in Denmark who have migraine on a few days each month and have used triptan rescue medicines.
Aarhus CAges 18–65 - NCT05987592Recruiting
Wellness and brain education for migraine relief
This study tests an 8-week online program that combines brain education and wellness skills to help people with migraine. It aims to reduce headache-related disability and improve quality of life.
Cambridge, MassachusettsAges 18 years+ - NCT07719608Recruiting
MySalvia system for resistant migraine
This trial tests a device called MySalvia that is implanted in the head to reduce migraine attacks. It is for people whose migraines have not improved with at least three different preventive treatments.
Newnan, GeorgiaAges 22–84 - NCT07652034Recruiting
Tracking migraine relief after a minimally invasive artery procedure
This study follows adults who undergo a procedure called middle meningeal artery embolization—a minimally invasive treatment that blocks blood flow to a specific artery thought to trigger migraines. The trial simply tracks your symptoms and quality of life before and after the procedure to understand how well it works.
Tacoma, WashingtonAges 18–64 - NCT07223008Recruiting
Bilateral artery embolization for chronic migraine
This trial tests a procedure called bilateral middle meningeal artery embolization to see if it reduces chronic migraine symptoms in people who haven't found relief from other treatments. It's for those with frequent, disabling migraines that affect both sides of the head.
Baltimore, MarylandAges 18–80 - NCT07159750Recruiting
Study on new migraine drugs in real life
This study tracks how well new migraine medications (like Aimovig, Emgality, Ajovy, Vyepti, Qulipta, and Nurtec) work in everyday use. It may help you and your doctor understand if these treatments are a good option for your migraines.
Miami, FloridaAges 18 years+ - NCT07015411Recruiting
Neuro supplements for migraine prevention
This trial tests whether a combination of vitamins and supplements can help prevent migraines. It's for adults who have migraines often (at least 6 days per month) and want to try a non-drug option.
MechelenAges 18–75 - NCT06938178Recruiting
EEG markers of mindfulness for migraines
This trial uses EEG (brain wave) tests to see if mindfulness therapy, added to your regular treatment, helps people with frequent migraines (8–14 headache days per month). You will have brain scans before and after mindfulness sessions to look for changes that show it's working.
MilanAges Any age - NCT06603558Recruiting
Preventing migraines with atogepant for Korean adults
This study tests a once-daily pill, atogepant, to see if it safely prevents chronic or episodic migraines in Korean adults. It's meant for people whose doctor has already prescribed the pill for migraine prevention.
Busan, Busan Gwang YeogsiAges 19 years+ - NCT06409832Recruiting
Study of rimegepant for migraine prevention
This study tests a medicine called rimegepant to see if it helps prevent migraines. If you have migraine at least 4 days per month, this might be for you.
Florence, FlorenceAges 18 years+ - NCT06203873Recruiting
Comparing biodegradable vs. metal heart-hole closures for migraine
This trial compares two types of devices (biodegradable vs. metal) to close a small hole in the heart (PFO) in people who have migraine not controlled by usual treatments. It aims to see which device works better to reduce migraine attacks.
Beijing, Beijing MunicipalityAges 18–65 - NCT05903027Recruiting
Testing gepant migraine treatment for better side effects
This trial studies how well a “gepant” medicine works for different types of migraine and how tolerable it is. It may help if you have frequent migraines and you can keep a headache diary as the study asks.
FlorenceAges 18 years+ - NCT05415020Recruiting
Behavior program for chronic migraine
This trial tests a behavioral (talk/skills-based) program to help people with chronic migraine. It may help reduce migraine frequency or improve day-to-day coping.
Phoenix, ArizonaAges 18 years+ - NCT07754266Recruiting
Headache, ear, and dizziness registry
This study collects information from people who have headaches, ear problems, dizziness, or sinus issues to better understand these symptoms and how they relate to migraine. Your participation may help improve future treatments and diagnosis.
North Kingstown, Rhode IslandAges 18 years+ - NCT06684249Recruiting
Comparing nerve block and Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (injection near the nerves in the head) and Botox injections. It aims to see which one works better to reduce headache days and improve quality of life.
Zagazig, Sharqia ProvinceAges 18–65 - NCT04628429Recruiting
Study CGRP blocker effects on migraine and body nerve function
This study tests a CGRP-blocking antibody to see how it affects migraine symptoms and the body’s automatic (involuntary) nerve functions. It may help people with migraine who have already tried several preventive medicines.
ViennaAges 18–64 - NCT07573488Recruiting
Sleep, Stress, and Migraine: Observation and Training Study
This study explores how sleep and stress affect migraine headaches and tests whether improving sleep habits can help reduce migraines. You'll be observed and taught strategies over several months while researchers track your headaches and sleep patterns.
ZurichAges 18–65
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Migraine trials by city
Studies with a site in or near these metro areas.
Migraine trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for migraine?
- Yes. Clin2 currently lists 191 recruiting migraine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a migraine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a migraine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.