Zoledronate for bone pain in children with chronic recurrent multifocal osteomyelitis
Treatments studied
Part of Bones, joints & muscles, Infections clinical trials.
This trial tests if zoledronate, a medicine that strengthens bones, can reduce pain in children with CRMO (a condition causing repeated bone inflammation). It compares zoledronate to a placebo (inactive treatment) to see if it helps after 12 weeks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 4 and 16 years old
- You have been diagnosed with CRMO by a doctor and have active bone pain or inflammation
- You have tried NSAIDs (like ibuprofen) for at least 4 weeks without enough relief
- You had a dental checkup within the last 3 months and any needed dental work is done
- You have not had treatment with bisphosphonates (like zoledronate) or biologic drugs in the last 6 months
- You are not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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