Clin2
NCT07684287Possibly a fitNot yet recruiting

Sirolimus for progressive or symptomatic epithelioid hemangioendothelioma

Epithelioid Hemangioendothelioma

Treatments studied

Part of Cancer clinical trials.

This study tests sirolimus for people with a rare blood-vessel cancer called epithelioid hemangioendothelioma (EHE) that is growing or causing symptoms. The goal is to see if the drug can control the disease and improve symptoms. It's for people who can't have surgery to remove the cancer and need systemic treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • You must have a confirmed diagnosis of EHE that is progressive or symptomatic and not suitable for curative surgery.
  • You must have at least one measurable tumor that can be evaluated for response.
  • You must have adequate organ function (kidney, liver, bone marrow, and blood clotting).
  • You must have controlled blood sugar and cholesterol levels.
  • You must be willing to use effective contraception during treatment and for 6 months after.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06408441Recruiting
EHE registry for rare adult cancers

This study collects information from European hospitals on people with epithelioid hemangioendothelioma (EHE), a rare tumor that grows in blood vessels. Joining this registry helps doctors learn more about the disease and improve care for others.

Graz, Graz
NCT05925023Recruiting
Sirolimus for warm autoimmune hemolytic anemia after steroid failure

This trial studies sirolimus in adults with “warm” autoimmune hemolytic anemia (or Evans syndrome) when steroids have not worked or the anemia has returned. It may help control the immune attack on red blood cells, but there are specific safety checks for liver health and infections.

Beijing, Beijing Municipality
NCT07518277Not yet recruiting
Steroid plus sirolimus for mild autoimmune hemolytic anemia

This trial tests whether adding sirolimus (a medication that calms the immune system) to standard steroid treatment is better than steroids alone for people newly diagnosed with mild autoimmune hemolytic anemia (AIHA). It may help control the disease with fewer side effects.

Beijing, Shuangfuyuan, NO I.
NCT07165886Recruiting· Phase 2/Phase 3
Study of sirolimus and octreotide for advanced neuroendocrine tumors

This trial tests a combination of two drugs, sirolimus and octreotide, for people with advanced neuroendocrine tumors in the digestive system that cannot be removed by surgery and are not making excess hormones. The goal is to see if this combination can help control the tumors.

Beijing, Beijing Municipality
NCT07104331Recruiting· Phase 2
Testing nab-sirolimus for epithelioid hemangioendothelioma

This trial is studying a drug called nab-sirolimus for people with a rare type of vascular tumor called epithelioid hemangioendothelioma (EHE) that is growing or causing symptoms. The goal is to see if the drug can help control the tumor.

Stanford, California
NCT05351216Recruiting
Sirolimus safety with routine vaccines for a rare blood vessel tumor

This trial studies how the medicine sirolimus affects children’s response to routine vaccines during treatment for kaposiform hemangioendothelioma (KHE). It compares vaccinated KHE patients taking sirolimus with healthy children getting the same vaccines.

Shanghai, Shanghai Municipality

Hear when a new Epithelioid Hemangioendothelioma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.