Fluid response test in critically ill patients with sepsis
Part of Infections clinical trials.
This study looks at how the body responds to extra fluids in patients with severe infections (sepsis) who are on a breathing machine. It aims to understand how fluids affect blood flow and congestion to improve treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a severe infection causing low blood pressure that needs medication to support it.
- You are on a breathing machine (mechanical ventilation).
- You have a central line (a special IV in a large vein near the heart) and an arterial line (a small tube in an artery) in place.
- A simple test called passive leg raising shows your heart can handle more fluids.
- You are 18 years or older and not pregnant.
- You do not have conditions like unstable spine fractures, high pressure in the brain, or poor blood flow to your legs that would make the leg test unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new way to see if giving more fluids helps patients with septic shock, a severe infection that drops blood pressure. It uses a quick heart ultrasound to check if fluids will improve blood flow, aiming to guide better treatment.
This study is testing two different ways of giving intravenous fluids to patients with sepsis (a severe infection) who have low blood pressure. It aims to find out whether giving more or less fluid is better for recovery.
This trial compares the use of a simple ultrasound test of the lungs and heart to help doctors decide how much fluid to give adults with septic shock. The goal is to find the most accurate way to guide treatment, which could lead to better recovery.
This study compares two monitoring methods to help doctors give the right amount of fluids to children with septic shock. It aims to avoid giving too much or too little fluid, which can affect recovery.
This study tests a computer software that helps doctors decide how much fluid to give patients in septic shock. It aims to improve blood pressure and oxygen delivery without causing fluid overload.
This study looks at how the body uses energy (metabolism) in people with septic shock. It collects information from standard monitoring during a fluid challenge (a small IV fluid test) to find patterns that might help doctors better understand and treat septic shock.
Hear when a new Septic Shock trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.