Verapamil for blood sugar issues in cystic fibrosis
Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.
This study is testing whether a common blood pressure medication called verapamil can help regulate blood sugar in people with cystic fibrosis who have elevated glucose levels. It is a phase 2 trial that aims to see if verapamil can delay or treat diabetes in this population.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 14 years or older.
- You have a confirmed diagnosis of cystic fibrosis (CF)
- You have pancreatic insufficiency, meaning you need to take enzymes with meals to help digest food.
- You have been diagnosed with either abnormal glucose tolerance (AGT) or CF-related diabetes (CFRD) within the last 3 months.
- You are willing to take up to 360 mg of verapamil by mouth daily, and if you take Trikafta, you're willing to adjust the dose.
- You are not currently on insulin or other diabetes medications, and you haven't had a CF flare-up needing IV antibiotics in the last month.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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