Clin2
NCT07692217Possibly a fitRecruiting

Joint health study for severe hemophilia A patients on new therapies

Hemophilia AFactor VIII (FVIII)

Part of Blood & lymphatic, Genetic & congenital clinical trials.

This study checks joint health and bleeding risk in people with severe hemophilia A who are taking newer factor VIII treatments or emicizumab. It uses ultrasound and blood tests to see how well these therapies protect joints.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
60 people
Ages
6 months and older
Study type
Observational

Who can take part

  • You have moderate or severe hemophilia A.
  • You are currently on a regular treatment (prophylaxis) with either emicizumab or efanesoctocog alfa for at least 2 months.
  • You are older than 6 months.
  • You do not have an active factor VIII inhibitor (more than 0.5 Bethesda units).
  • You do not have any other bleeding disorder besides hemophilia A.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06816953Enrolling by invitation
Joint health in severe hemophilia A with prophylaxis

This study is looking at how well joint health can be tracked in people with severe hemophilia A who are receiving regular factor VIII treatment. It uses special markers in the blood and ultrasound to check for early joint changes.

Bangkok, Patumwan
NCT07582276Recruiting
Bone health in men with severe hemophilia a on two treatments

This study looks at how two different hemophilia A treatments affect bone health over time. It tests if one medicine is better at keeping bones strong than the other.

Little Rock, Arkansas
NCT06938659Not yet recruiting· Phase 2/Phase 3
Comparing two low-dose preventives for severe hemophilia a

This trial compares two low-dose medicines to prevent bleeding episodes in people with severe hemophilia A: a newer medicine (emicizumab) versus the standard factor VIII treatment. It may help find a more convenient or effective way to reduce bleeding.

Dhaka
NCT05022459Recruiting
Prevent bleeding in kids with Hemophilia A who play sports

This study compares two ways to prevent bleeding in people with Hemophilia A while they play sports. It looks at whether factor VIII or emicizumab prophylaxis helps reduce bleeding during higher-risk sports activities.

Little Rock, Arkansas
NCT07838194Not yet recruiting· Phase 3
Preventive treatment for hemophilia A in infants and children

This study tests a new preventive treatment (NXT007) to help stop bleeding episodes in infants and children with hemophilia A. It aims to see if this treatment reduces the number of bleeds and improves quality of life.

NCT06809972Recruiting
Understanding joint lining changes on ultrasound in hemophilia

This study uses ultrasound to check if thickened joint lining (synovium) in people with severe hemophilia is a sign of active inflammation or just a harmless leftover. It may help doctors decide whether to treat or watch these joints.

Utrecht

Hear when a new Hemophilia A trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.