Clin2
NCT07692490Possibly a fitRecruiting

Avoiding cooling after warm machine perfusion for liver transplant

Liver Transplantation (LT)Ischemia-Reperfusion InjuryEarly Allograft Dysfunction

Part of Heart & circulation clinical trials.

This study tests whether a donor liver kept on a special warm machine can be transplanted safely without needing to cool it down first. It is for adults receiving their first liver transplant who have stable liver disease (not acute failure).

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
170 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You are listed for your first liver transplant.
  • Your donor liver will be kept on a machine that keeps it warm and nourished (called normothermic machine perfusion).
  • You are able to understand and sign a consent form.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07674394Not yet recruiting
Testing new ways to check liver health during machine perfusion

This study is testing whether a quick look at small liver samples during cold machine perfusion can help doctors tell if the organ is healthy enough for transplant. If it works, this method could improve transplant success by catching problems early.

Milan
NCT03946852Not yet recruiting
Testing a new blood-boost method for liver transplants after cardiac death

This study tests whether a special way of moving blood through the donor abdomen before surgery can improve liver (and other organ) transplant quality. It may help because doctors can check how well the liver seems to be working before it’s actually used.

NCT07585890Recruiting
Liver Transplant Outcomes With Machine Preservation in Europe

This study collects information about how livers do after transplantation when they've been preserved using machine perfusion—a technique that keeps donor livers in better condition before surgery. Researchers want to understand which preservation methods work best to improve transplant success across Europe.

Torino
NCT06418165Recruiting
Cooled oxygenated machine perfusion for liver transplant

This study tests a new way to preserve donated livers using a machine that keeps the organ cool and oxygenated before transplant. It may help improve how well the liver works after the surgery.

Vienna
NCT06950398Not yet recruiting· Phase 2
Testing discarded livers with machine perfusion

This trial tests if a machine that pumps warm oxygenated blood through livers that were considered unsuitable for transplant can help doctors decide if they are actually safe to transplant. If so, it could increase the number of available livers for people waiting for a first liver transplant.

Clichy
NCT07595627Not yet recruiting
Machine-Preserved Liver Transplants for End-Stage Liver Disease

This trial tests a special preservation machine that keeps donor livers cold and functioning during transport before transplant. The goal is to improve how well donated livers work after transplantation and reduce complications.

São Paulo, São Paulo

Hear when a new Ischemia Reperfusion Injury trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.