Machine preservation for donated livers before transplant
Part of Digestive system, Heart & circulation clinical trials.
This study tests a new way to preserve donated livers using a special machine that keeps the liver cool and pumps fluid through it before transplantation. This may help the liver stay in better condition for the recipient, which could improve transplant success.
Summary written for real people, not researchers, by Clin2.
Who can take part
- The liver comes from a donor who has been declared brain-dead and is considered an 'extended criteria donor' (a donor whose liver may be less than ideal but still usable).
- The donor must be 18 or older, and the family has given permission for organ donation.
- The donor tests negative for certain infections (HTLV, HIV, Chagas disease, and hepatitis B and C).
- You are 18 or older and are getting your first liver transplant because of end-stage liver disease.
- You do not have severe or moderate fatty liver disease in the donated liver, and the donor is not classified as 'ideal' by the study's strict criteria.
- You do not have complex portal vein blood clots, are not getting a combined organ transplant, are not being re-transplanted, do not have acute liver failure, have a MELD score of 30 or less, and have not had multiple prior liver or bile duct surgeries.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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