Testing a heart shunt to reduce symptoms in advanced heart failure
Part of Heart & circulation clinical trials.
This trial tests a device called the V-Wave Shunt to see if it can reduce lung congestion and improve symptoms in people with advanced heart failure and a reduced ejection fraction (a measure of how well the heart pumps). It may help if you have severe symptoms despite taking all recommended heart medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have heart failure with a reduced ejection fraction (≤40%) and have had heart failure for at least 6 months.
- You have severe symptoms (NYHA Class III) like shortness of breath with minimal activity.
- You take all recommended heart failure medications (such as an ARNI, ACE inhibitor, ARB, beta blocker, SGLT2 inhibitor, and diuretics as needed) at stable doses for at least one month.
- You have had a heart failure hospitalization or an emergency room visit for heart failure lasting at least 6 hours within the past year, or you have a high BNP or NT-proBNP level (a sign of heart stress).
- You can walk at least 100 meters but no more than 450 meters in 6 minutes.
- You do not have conditions like a recent heart attack, stroke, blood clots, severe lung problems, or kidney failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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