Clin2
NCT07699328Worth exploringRecruiting

Study of VRN110755 for EGFR-mutant lung cancer

EGFR-Mutant Non-Small Cell Lung Cancer

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new oral targeted therapy (VRN110755) for people with EGFR-mutant lung cancer. It is for those whose cancer has advanced or spread, and who either have not been treated yet or who stopped responding to previous EGFR pills.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
315 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older (19 in South Korea) and can swallow capsules.
  • You have advanced or spread lung cancer with an EGFR gene change (mutation) found in a tissue or blood test.
  • Your cancer either got worse after treatment with an EGFR pill, or you haven't had any treatment yet, depending on which group you join.
  • You have at least one tumor outside your brain that can be measured on scans.
  • You are generally up and about (ECOG 0 or 1) and agree to use birth control if needed.
  • You do not have certain other gene changes like EGFR exon 20 insertion, active infections, unstable heart disease, or lung scarring.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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