Comparing two injection devices for SHR-1703 in healthy volunteers
Treatments studied
Part of Lungs & breathing clinical trials.
This trial tests two ways to give the study drug SHR-1703: a pre-filled syringe and an autoinjector. Healthy participants will help see if both devices work safely and similarly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old.
- Your body mass index (BMI) is between 19 and 26, and you weigh between 50 and 80 kg.
- You are in good general health with no major medical conditions, based on physical exams, blood and urine tests, heart tracing (ECG), abdominal ultrasound, and chest X-ray.
- If you are a woman able to have children, or a man with a partner who can, you must use effective birth control from the start of the study until 14 months after the last dose, and not donate sperm or eggs.
- You have not smoked heavily (less than 5 cigarettes per day) or had more than a small amount of alcohol (like one beer or glass of wine, no more than twice a week) in the last 6 months, and have no history of drug abuse.
- You have not taken any prescription, over-the-counter, or herbal medicines (except routine vitamins or occasional pain reliever) in the month before dosing.
- You have not donated a lot of blood (400 mL or more) in the last month or received a blood transfusion in the last 2 months.
- You have not had a live vaccine in the last month or plan to get one during the study.
- You are not pregnant, breastfeeding, or planning a pregnancy, and have a negative pregnancy test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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