Psilocybin and therapy for depression with trauma
Treatments studied
Part of Injuries & trauma, Mental health clinical trials.
This trial tests psilocybin (a compound from certain mushrooms) combined with a structured therapy to see if it helps people with depression linked to trauma. It focuses on how the treatment affects the connection between the gut and brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have been diagnosed with major depression and also have significant trauma-related symptoms.
- You are currently taking only one antidepressant (an SSRI) and have been on it for at least 6 weeks.
- You do not have a history of bipolar disorder, psychosis, or a current substance use problem.
- You are willing to attend all study visits and follow safety guidelines, including using contraception if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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