Brain activity study during light sedation
Treatments studied
This study uses brain scans (fMRI) to see if people who are lightly sedated can still think or respond. Researchers want to understand 'covert consciousness' during sedation with two common medicines, dexmedetomidine and ketamine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a healthy adult with no major medical problems (ASA-1 status).
- You are right-handed.
- Your body mass index (BMI) is under 30.
- You have played tennis or another racquet sport at least 30 times in your life.
- You speak English.
- You have no metal in your body, are not pregnant or breastfeeding, and are not claustrophobic.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study explores how people recover after being given a common sedative called dexmedetomidine. It may help doctors better understand and manage recovery from sedation.
This study uses focused ultrasound to stimulate a deep brain region and see if it can help people wake up faster from anesthesia. Healthy volunteers will be sedated and monitored while the ultrasound is applied.
This trial tests how anesthesia affects brain activity in people with drug-resistant epilepsy who need brain electrode monitoring. It may help us understand consciousness and improve anesthesia safety.
This study uses MRI scans to see how two common sedatives, ketamine and propofol, affect brain activity. It may help explain how these drugs work differently in the brain.
This study looks at how the brain changes when people go under general anesthesia. It includes children having surgery and healthy adults, which may help doctors understand consciousness better.
This study tests whether we can safely and reliably induce dreaming in healthy adults using anesthesia and brain wave (EEG) monitoring. You would be given a low dose of an anesthetic and then monitored as you fall asleep to see if dreams can be triggered.
Hear when a new Healthy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.