First human trial of CTX-187 for healthy people and those with chronic infection
Part of Infections, Lungs & breathing clinical trials.
This trial tests a new drug called CTX-187 in two groups: healthy volunteers (Parts A and B) and people with chronic lung infection from bronchiectasis (Part C). It helps find the right dose and checks safety.
Summary written for real people, not researchers, by Clin2.
Who can take part
- For healthy volunteers: You are between 18 and 65 years old, in good health, with a BMI between 18 and 32.
- You must weigh more than 50 kg (about 110 pounds).
- For people with bronchiectasis: You are between 18 and 75 years old and have a confirmed diagnosis of bronchiectasis.
- You have had a Pseudomonas aeruginosa infection in your lungs in the past year and still have it now.
- You are not taking new antibiotics for Pseudomonas that started in the last 3 months.
- You do not have cystic fibrosis, active tuberculosis, or unstable heart, lung, or other conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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