Tracking optic nerve swelling in traumatic brain injury rebound
Part of Brain & nervous system, Injuries & trauma clinical trials.
This study checks if ultrasound measurements of the optic nerve sheath can help guide treatment for brain swelling after a head injury. It aims to make treatments safer and more effective for patients with traumatic brain injury.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a blunt head injury (not a penetrating wound).
- Your initial brain injury severity score was 12 or less, OR you had a score of 13-15 but with signs of brain swelling on a CT scan.
- Your doctor decided to start you on a medicine called mannitol (given through an IV) to reduce brain swelling.
- You do not have any eye conditions that would prevent measuring the optic nerve sheath, and you are not pregnant.
- You do not have plans for brain surgery within 48 hours, and you do not have severe kidney problems or other contraindications to mannitol.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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