Measuring optic nerve sheath in brain injury rebound study
Part of Brain & nervous system, Injuries & trauma clinical trials.
This trial tests if measuring the optic nerve sheath (the lining around the eye nerve) can help track pressure in the brain after a head injury, especially when patients need a medicine called mannitol to reduce swelling. It may help doctors make better decisions for patients with traumatic brain injury.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You had a head injury that caused a brain bruise or bleeding
- Your Glasgow Coma Scale (a measure of consciousness) is 12 or less at the hospital, or 13-15 with signs of brain swelling on a CT scan
- Your doctor decided to start you on a medicine called mannitol to lower brain pressure
- You do not have eye problems like glaucoma, prior eye surgery, or eye injuries that would affect the measurement
- You are not pregnant, and you do not have any reason you cannot receive mannitol (like high sodium or kidney problems)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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