Switching to oral weight-loss pills to prevent regain after stopping GLP-1 injections
Treatments studied
Part of Hormones & metabolism clinical trials.
This study is for people who have lost weight using GLP-1 injections (like semaglutide or tirzepatide) and are thinking about stopping them. It tests whether switching to an oral weight-loss medication can help you keep the weight off.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- Your weight has put you in the obesity range (BMI 30 or higher).
- You are currently taking or recently stopped (within 8 weeks) an injectable GLP-1 medicine like semaglutide or tirzepatide.
- You have lost at least 10% of your body weight on that medicine.
- You must live in Massachusetts and be willing to take part in a study with random assignment.
- No diabetes, no history of pancreatitis, no organ transplant, and no severe mental health conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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