Clin2
NCT07738068Possibly a fitNot yet recruiting

Progesterone support for unexplained infertility

InfertilityFemale InfertilitySubfertilityInfertility PrimaryInfertility SecondarySubfertility, Female

Part of Women’s health & pregnancy clinical trials.

This trial tests if giving progesterone after ovulation improves pregnancy chances for people with unexplained infertility. It is for those who have been trying to conceive for at least one year and are currently waiting before more advanced treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
640 people
Ages
18 years to 43 years
Study type
Interventional

Who can take part

  • Been trying to get pregnant for at least one year without success
  • Regular menstrual cycles between 21 and 35 days
  • Sperm count of 10 million or more motile sperm per milliliter
  • A fertility score (Hunault) of 30% or higher
  • Willing to continue trying on your own for at least six more months before starting other treatments
  • Age 18 or older and BMI under 45

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07508657Not yet recruiting· Phase 4
Progesterone after letrozole for intrauterine insemination

This trial tests whether taking progesterone after a type of fertility treatment called IUI can improve success rates. The study focuses on people who are using a drug called letrozole to stimulate the ovaries.

Copenhagen
NCT05899010Recruiting· Phase 3
Micronized progesterone for frozen embryo transfers

This Phase 3 study tests whether adding micronized progesterone during frozen embryo transfer cycles helps support embryo implantation and pregnancy. You may benefit if your care team is already preparing the uterus with hormone therapy for a blastocyst transfer.

Barcelona
NCT02357654Recruiting· Phase 4
Hormone treatment to support the uterine lining in IVF cycles

This trial tests whether a hormone called GnRH can help support the lining of the uterus after IVF, ICSI, or frozen embryo (FET) embryo transfer. It may be offered around the time of embryo transfer to improve the chances of a successful implantation.

Hasbrouck Heights, New Jersey
NCT03859921Recruiting· Phase 3
Dydrogesterone pill support during natural-cycle embryo transfer

This Phase 3 study tests whether taking an oral progesterone-like medicine (dydrogesterone) during the “luteal phase” after a natural-cycle frozen embryo transfer can improve support for implantation. It may help couples who are using their own embryos in a natural (hormone-sparing) cycle after thawing.

Hong Kong, Hong Kong
NCT07340827Recruiting· Phase 3
Comparing two fertility drugs in Japanese women with hormone deficiency

This study tests if a combination of two hormone drugs (follitropin alfa/lutropin alfa) works as well as another drug (hMG) for Japanese women with low LH and FSH levels who are doing in vitro fertilization (IVF). The goal is to help them produce eggs for pregnancy.

Akita, Akita
NCT05080569Recruiting· Phase 4
Extra support after IUI for couples with unclear infertility

This study tests whether adding support in the period after ovulation (the “luteal phase”) helps people who are starting IUI (intrauterine insemination) because their infertility is unexplained. It’s designed to see if the added care improves chances when mild ovarian stimulation is used.

Utrecht

Hear when a new Infertility trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.