Dydrogesterone pill support during natural-cycle embryo transfer
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This Phase 3 study tests whether taking an oral progesterone-like medicine (dydrogesterone) during the “luteal phase” after a natural-cycle frozen embryo transfer can improve support for implantation. It may help couples who are using their own embryos in a natural (hormone-sparing) cycle after thawing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are under 43 years old when your IVF stimulation started
- You are doing a frozen embryo transfer using your own early embryos or blastocysts after thawing
- You must be using a natural-cycle approach (not a hormone replacement cycle)
- You must not use donor eggs or donor embryos
- You must not plan preimplantation genetic testing on the embryos
- If you have a blocked, fluid-filled fallopian tube (hydrosalpinx), it must have been treated with surgery before transfer
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial checks if taking extra hormones after a frozen embryo transfer (called luteal support) is needed when using your natural cycle. It may help improve pregnancy chances.
This study is testing whether starting a frozen embryo transfer during your natural cycle (after ovulation) is more convenient than the usual schedule. You will take progesterone (400 mg twice a day) and have one embryo transferred. It is for people using donor eggs who have regular cycles.
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