Clin2
NCT07738302Possibly a fitNot yet recruiting

Cryotherapy and dexamethasone for pain after root canal

Post Operative Pain

Part of Pain clinical trials.

This study tests whether applying cold therapy or a steroid medicine inside the tooth after a root canal can reduce pain after the procedure. If you have a painful, infected tooth needing a root canal, this might help you feel more comfortable afterward.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
60 people
Ages
20 years to 50 years
Study type
Interventional

Who can take part

  • You are in generally good health (no serious medical conditions)
  • You are between 20 and 50 years old
  • You have a tooth with irreversible pulpitis and apical periodontitis (infection and inflammation at the root tip)
  • Your tooth has no visible bone infection (no periapical radiolucency)
  • The root canals are open (not blocked)
  • You agree to participate and sign a consent form

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07764666Enrolling by invitation
Cooling rinse for molar pain after root canal treatment

This study tests whether using a chilled saline rinse during a root canal treatment can reduce pain after the procedure. It compares two standard rinses, with and without cooling, to see which is more comfortable.

Cairo, Cairo Governorate
NCT07264829Not yet recruiting
Cold therapy for reducing pain during root canal treatment

This trial is testing two cold-therapy techniques applied directly to the tooth nerve to see which one better reduces pain during a root canal treatment. It aims to make the anesthesia work faster and more effectively, so you feel less discomfort during the procedure.

Karachi, Sindh
NCT06894069Not yet recruiting· Early Phase 1
Steroid inside a root canal for less tooth pain

This study looks at whether putting a common steroid medicine (dexamethasone) inside the tooth during a root canal can reduce pain after the procedure. If you have a painful tooth with an inflamed nerve, this treatment might help you feel better faster.

NCT07733700Not yet recruiting
Cold treatment for tooth pain after root canal re-treatment

This study tests if applying cold therapy to a tooth after a second root canal procedure can reduce pain, and looks at how it affects certain natural chemicals in the body. It may offer a simple, drug-free way to manage discomfort after the treatment.

Antalya, ALANYA
NCT07036237Enrolling by invitation
Comparing pain relief rinses after root canal

This trial tests whether rinsing the tooth with either tramadol (a pain reliever) or dexamethasone (a steroid) after a root canal reduces pain better. It is for people with a single-rooted tooth that has a very painful, inflamed nerve.

Karachi, Sindh
NCT06584188Not yet recruiting· Phase 2
Cold spray during root canal for less post-treatment pain

This study tests a special cold spray (cryoagent) applied during root canal treatment to see if it reduces pain after the procedure. If you're having root canal pain, this might help make recovery more comfortable.

Cairo

Hear when a new Post Operative Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.