Clin2
NCT07738302Possibly a fitNot yet recruiting

Cold therapy and dexamethasone for tooth pain after root canal

Post Operative Pain

Part of Pain clinical trials.

This study compares two methods to reduce pain after a root canal: applying cold (cryotherapy) and using a steroid medicine called dexamethasone. It aims to find which approach works better for managing post-procedure discomfort.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
60 people
Ages
20 years to 50 years
Study type
Interventional

Who can take part

  • You are generally healthy (classified as ASA I or II).
  • You are between 20 and 50 years old.
  • You have been diagnosed with severe tooth pain from an infected pulp (irreversible pulpitis) and inflammation at the root tip (apical periodontitis).
  • You have no signs of infection at the root tip on x-rays (no periapical radiolucency).
  • Your tooth has not been previously treated with a root canal and has no history of trauma.
  • You agree to participate by signing an informed consent form.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06785753Recruiting· Phase 2
Cold therapy for tooth pain after root canal

This study tests whether applying cold (cryotherapy) to the tooth and gum can reduce pain after root canal treatment in people with severe tooth pain. It aims to find a safe, drug-free way to manage pain during the procedure.

Rawalpindi, Punjab Province
NCT07764666Enrolling by invitation
Cooling rinse for molar pain after root canal treatment

This study tests whether using a chilled saline rinse during a root canal treatment can reduce pain after the procedure. It compares two standard rinses, with and without cooling, to see which is more comfortable.

Cairo, Cairo Governorate
NCT07357233Recruiting
Comparing two methods for root canal pain relief in lower molars

This trial compares two different ways of cleaning and shaping the inside of a tooth (root canal) to see which one causes less pain afterward. It is for people with a specific type of tooth infection in a lower back molar.

Alexandria
NCT06894069Not yet recruiting· Early Phase 1
Steroid in root canal for pain after treatment

This study tests whether placing a steroid medication (dexamethasone) inside the root canal during a root canal procedure helps reduce pain afterward. If you have a tooth with an inflamed nerve and some tenderness, this trial may help control your discomfort.

NCT06584188Not yet recruiting· Phase 2
Cooling treatment for tooth pain after root canal

This trial tests whether a special cooling treatment (cryotherapy) can reduce pain right after a root canal for a badly infected lower premolar. If you are healthy and not on painkillers, this may help you feel better faster.

Cairo
NCT07036237Enrolling by invitation
Comparing pain relief rinses after root canal

This trial tests whether rinsing the tooth with either tramadol (a pain reliever) or dexamethasone (a steroid) after a root canal reduces pain better. It is for people with a single-rooted tooth that has a very painful, inflamed nerve.

Karachi, Sindh

Hear when a new Post Operative Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.