Clin2
NCT07743541Possibly a fitNot yet recruiting

TUB-040 for recurrent uterine cancer after chemotherapy and immunotherapy

Uterine Endometrial Cancer

Part of Cancer, Women’s health & pregnancy clinical trials.

This trial tests a new drug called TUB-040 for people with uterine cancer (specifically serous or endometrioid type) that has returned or grown after standard treatments like chemotherapy and immunotherapy. The drug is designed to target and kill cancer cells with less harm to healthy cells, and the study hopes to help patients who have run out of standard options.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a type of uterine cancer called serous or endometrioid, and it has come back or grown despite treatment.
  • You have already had at least one round of chemotherapy (platinum-based) and one round of immunotherapy (like pembrolizumab or dostarlimab).
  • Your cancer must show growth on a scan after your last treatment.
  • You are at least 18 years old and able to do daily activities with little or no help.
  • You need to have a tissue sample available for testing, or be willing to have a new biopsy.
  • You must have normal organ function (liver, kidneys, blood counts) and no major health conditions that would make the trial risky.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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