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NCT07736937Possibly a fitRecruiting

Study of TUB-040 with Standard Drugs for Ovarian Cancer

Ovarian Cancer

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study tests a new medicine called TUB-040, given together with standard ovarian cancer drugs like carboplatin and bevacizumab. It is for women with ovarian cancer that has returned after responding to platinum-based chemotherapy and is growing again. The goal is to see if this combination can help control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
72 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are a woman aged 18 or older.
  • Your ovarian cancer is a specific type (high-grade serous or endometrioid) and has come back after responding to platinum-based treatment, but not within 6 months of finishing that treatment.
  • You have had 1 or 2 prior lines of platinum therapy, and your cancer has grown according to scans.
  • You are in generally good health (able to do light activities) and have adequate kidney, liver, and blood function.
  • You must have a tumor sample (from a previous biopsy or surgery) available for testing, or be willing to have a new biopsy.
  • You have been previously treated with a PARP inhibitor if your tumor had a BRCA mutation or was HRD positive and the drug was available.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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