How the liver processes medicines in cirrhosis
Part of Digestive system clinical trials.
This study looks at how well your liver processes certain common medicines if you have cirrhosis. It helps doctors understand how to give the right dose of medicines to people with liver disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a diagnosis of cirrhosis (liver scarring) confirmed by tests, scans, or a biopsy.
- Your liver disease is not too severe (MELD score 30 or less).
- Your kidneys work well enough (a blood test shows adequate kidney function).
- You have not had a bad reaction to any of the study medicines (caffeine, warfarin, esomeprazole, metoprolol, midazolam).
- You have not taken certain medicines or substances (like some antibiotics, antifungals, or herbal products) that could interfere with the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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