Testing a pill's safety and effect on mosquitoes in healthy adults
Part of Infections clinical trials.
This study tests a new pill called lotilaner for safety and how well it works to kill mosquitoes that carry malaria. It is for healthy adults in Mali and may help future malaria prevention efforts.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 55 years old.
- You must weigh at least 50 kg (110 lbs) and have a body mass index between 18 and 32.
- You must live in the study area in Mali.
- You must be in good health overall, with no major medical conditions.
- You must not be pregnant, breastfeeding, or planning to become pregnant during the study.
- You must be willing to use contraception if you can become pregnant.
- You must not have malaria symptoms, but having the malaria parasite without symptoms is okay.
- You must not have used certain malaria medications or ivermectin recently.
- You must not smoke or use nicotine products for 90 days before the study.
- You must agree to follow study rules and stay in contact with the study team.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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