Clin2
NCT07760181Possibly a fitNot yet recruiting

Laser plus metformin cream for dark neck patches

Acanthosis Nigricans

Part of Skin clinical trials.

This study tests a laser treatment combined with a metformin cream for acanthosis nigricans, which causes dark, thick patches of skin on the neck. It aims to see if the combination is safe and improves the appearance of the skin.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
34 people
Ages
18 years to 50 years
Study type
Interventional

Who can take part

  • Men or women aged 18 to 50 years
  • Have acanthosis nigricans on the neck (diagnosed by a doctor or skin exam)
  • Medium to dark skin tone (types III to V)
  • Stable overall health for at least 3 months
  • Willing to follow the study schedule and come for follow-up visits
  • Not pregnant or breastfeeding, and no recent treatments or laser on the neck

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07696806Enrolling by invitation· Phase 4
Needle-assisted treatment for melasma using common skin medications

This trial tests a microneedling technique combined with three topical medications (metformin, tranexamic acid, and a modified Kligman's formula) to treat melasma, a common skin condition causing dark patches. The goal is to see if this approach safely and effectively reduces melasma in eligible women.

Tanta
NCT05362929Recruiting
Laser treatment for acne scars in darker skin tones

This study tests a new type of laser treatment for acne scars in people with darker skin tones. It aims to see if the laser is effective and safe for improving the appearance of scars.

Elmsford, New York
NCT07195539Enrolling by invitation
Laser and medicine for burn scar darkening

This trial tests if combining a special laser with a skin-lightening medicine can safely reduce dark marks from old burn scars.

Lahore, Punjab Province
NCT07779811Not yet recruiting· Phase 2
Metformin cream versus triple cream for skin darkening

This study compares a cream containing metformin to a triple combination cream for treating melasma, which causes brown patches on the face. The goal is to see which treatment is more effective in lightening these patches.

Karachi, Sindh
NCT06149780Recruiting
Laser treatment for dark spots after inflammation

This trial tests a special laser to see if it can safely lighten dark spots that appear after skin inflammation, especially in people with darker skin tones. It may help if you have these spots and they bother you.

Detroit, Michigan
NCT06942390Not yet recruiting· Phase 2
Comparing two creams for treating melasma in women

This study compares two different creams applied to the skin — metformin and ketotifen — to see which works better for treating melasma (dark patches on the face). If you are a woman with melasma, you may be eligible to join and receive one of these creams.

Hear when a new Acanthosis Nigricans trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.