Clin2
NCT07762586Worth exploringRecruiting

Neoadjuvant chemotherapy for muscle-invasive bladder cancer

Bladder Cancer

Treatments studied

Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.

This study looks at how well a standard chemotherapy given before surgery works for muscle-invasive bladder cancer. It aims to see if higher responses lead to better outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
60 people
Ages
18 years to 90 years
Study type
Interventional

Who can take part

  • You have been diagnosed with muscle-invasive bladder cancer that has not spread beyond the bladder.
  • You are fit to receive chemotherapy that is given before surgery.
  • You are willing to undergo surgery to remove your bladder as part of this study.
  • You are an adult (18 years of age or older).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07690878Not yet recruiting· Phase 2
Chemotherapy before bladder removal surgery for muscle-invasive bladder cancer

This trial tests giving chemotherapy before surgery to remove the bladder, to see if it can improve outcomes for patients with muscle-invasive bladder cancer. The treatment is personalized based on a lab test of your tumor cells, which may help make the therapy more effective.

Nanjing, Jiangsu
NCT06341478Recruiting
Bladder Cancer Tissue Study in Muscle-Invasive Patients

This study looks at tumor and blood samples from people with muscle-invasive bladder cancer to find markers that help predict how the disease will progress. It aims to improve personalized treatment for those with this specific stage of bladder cancer.

Milan, Mi
NCT06091124Recruiting· Phase 2
Immunotherapy plus chemo before surgery for neuroendocrine bladder cancer

This trial tests a combination of an immunotherapy drug (adebrelimab) with two chemotherapy drugs (etoposide and cisplatin) given before surgery for a rare, aggressive type of bladder cancer called neuroendocrine carcinoma. The goal is to see if this approach can shrink the tumor and improve outcomes.

Nanjing, Jiangsu
NCT07053722Not yet recruiting
Bladder preservation after neoadjuvant therapy for muscle-invasive bladder cancer

This study watches people with muscle-invasive bladder cancer who choose to keep their bladder after receiving neoadjuvant therapy (treatment before the main treatment). It aims to see how well bladder-preserving treatments like chemoradiation work over time.

NCT06537154Recruiting· Phase 2/Phase 3
Neoadjuvant therapy for bladder cancer with active surveillance

This trial tests whether people with muscle-invasive bladder cancer can safely avoid immediate surgery or radiation after a short course of chemotherapy. Instead, they would be closely monitored and only treated if the cancer comes back.

Vancouver, British Columbia
NCT07008833Not yet recruiting
Comparing surgery versus radiation and chemotherapy for muscle-invasive bladder cancer

This trial compares three standard treatments for muscle-invasive bladder cancer: bladder removal surgery, radiation combined with chemotherapy, or both. It aims to find which approach works best while preserving quality of life.

São Paulo, São Paulo

Hear when a new Bladder Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.