Mixed nut oral immunotherapy for children with multiple nut allergies
Part of Immune system & allergy clinical trials.
This study tests a treatment that slowly builds tolerance to multiple nut allergens (peanut and tree nuts) in children with allergies. It aims to reduce the risk of severe reactions from accidental exposure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Children aged 1 to 12 years.
- Confirmed allergy to at least two of these: peanut, cashew, walnut, hazelnut, or almond.
- Positive allergy test (skin prick test or blood test) for at least two of those foods.
- History of a mild-to-moderate allergic reaction to those foods during a food challenge (not a severe reaction).
- No history of very severe anaphylaxis, poorly controlled asthma, or other major health conditions (like eosinophilic GI disease or certain heart conditions).
- Not currently taking certain medications (like beta-blockers, ACE inhibitors, or oral steroids long-term).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a treatment program can help children and teenagers with peanut allergies develop tolerance to peanuts over time. The goal is to reduce the risk of serious allergic reactions if they accidentally eat peanuts.
This study compares two ways to manage food allergies in infants: giving tiny amounts of the allergen (oral immunotherapy) versus avoiding the allergen completely. It hopes to find out which approach helps young children outgrow their food allergies more effectively.
This study checks if you can stay allergy-free to cashew nuts after completing immunotherapy. It aims to see if your immune system can handle cashew protein without reacting.
This study tests if giving small, increasing amounts of cashew can help children outgrow their allergy. It may be an option for kids who are allergic to cashew and have had a clear allergic reaction in a food challenge.
This study collects blood (or uses already-collected blood) to learn why peanut, tree nut, and related food allergies happen and how they behave during challenges. It may help researchers better understand allergies and improve future care.
This study watches how milk and egg allergies change naturally over time or after oral immunotherapy (OIT) in children. It helps researchers understand how the immune system adapts, aiming to improve treatment for food allergies.
Hear when a new Food Allergy in Children trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.