Comparing two starting hormone doses for IVF in healthy younger women
This trial compares two starting doses of follicle-stimulating hormone (FSH) during in vitro fertilization (IVF) to see which works better. FSH helps your ovaries produce eggs, and the study aims to find the best dose for women with good fertility prospects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman under 35 years old (or an egg donor under 35).
- Your body mass index (BMI) is between 18 and 25.
- You have a normal ovarian reserve, meaning your antral follicle count is 8 or more and your AMH level is between 1.5 and 4.5 ng/mL.
- This is your first IVF cycle.
- You are using a specific stimulation protocol called PPOS with recombinant FSH and dydrogesterone.
- You need IVF with ICSI (injecting a single sperm into an egg) and plan to grow embryos to the blastocyst stage.
- You do not have polycystic ovary syndrome (PCOS), ovarian structural abnormalities, or ovarian endometriosis.
- You do not have medical conditions that could affect your response to stimulation.
- You do not need LH supplementation during stimulation.
- You and your partner do not have poor sperm quality or use surgically retrieved, frozen, or donor sperm.
- You do not need artificial oocyte activation or rescue ICSI.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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