Comparing two medicines plus light therapy for newborn jaundice
Part of Genetic & congenital clinical trials.
This study looks at whether adding a medicine (fenofibrate or phenobarbitone) to standard light therapy (phototherapy) can help lower bilirubin faster in newborns with jaundice. It compares the two medicines to see which one works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby must be a full-term newborn (born between 37 and 42 weeks of pregnancy) and between 24 hours and 14 days old.
- Your baby must weigh at least 2500 grams (about 5.5 pounds).
- Your baby must have jaundice caused by high bilirubin levels (15–20 mg/dL) that is not due to blood type problems or breakdown of red blood cells.
- Jaundice must not appear within the first 24 hours after birth.
- Your baby must not have other serious health conditions like infection, birth difficulties, birth defects, kidney or liver problems.
- Your baby must not have been given fenofibrate or phenobarbitone before, and the mother must not have taken phenobarbitone during pregnancy.
- Parents or legal guardians must give written permission for the baby to join the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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