Study of an injectable drug for major depressive disorder
Treatments studied
Part of Mental health clinical trials.
This study tests an investigational drug called brenipatide for major depressive disorder. It is given as a self-injection and is being compared to a placebo to see if it helps improve depression symptoms in people who are already on standard treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a diagnosis of major depressive disorder.
- You need to be on a stable dose of your current depression medication for at least 8 weeks.
- You must be willing to self-inject the study medicine at home and keep a diary.
- You cannot have certain mental health conditions like schizophrenia, bipolar disorder, borderline personality disorder, or an eating disorder.
- You cannot have type 1 diabetes or a history of diabetic emergencies.
- You must not have a recent history of moderate or severe substance or alcohol use disorder (within 6 months).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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